Nalecz Institute of Biocybernetics and Biomedical Engineering PAS, Warsaw, Poland

Challenges in biosensing technologies

CV: Dorota G. Pijanowska is a full professor at the Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences (IBBE PAS), where she received PhD and DSc degrees in 1996 and 2006, respectively. Currently, she is the deputy director for research at IBBE PAS. She received postdoctoral fellowship at the Biosensors Group, University of Twente, The Netherlands. In 2007 she has got a position of associate professor at the IBBE PAS and she became the head of Biosensors Lab and Department of Hybrid and Analytical Microbiosystems. In 2017 she was awarded with title of full professor. Her research interests include development, fabrication and characterization of chemical sensors and biosensors as well as micro total analysis systems (┬ÁTAS, lab-on-a-chip), and their biomedical applications.

Abstract: Talking about biosensing technologies (bioSTs) anyone can think of different research aspects, including micro/nanotechnologies, molecular recognition, bioaffinity, enzymatic reactions, as well as plenty of biochemical species and biomarkers to be determined. Regardless various points of view, bioSTs are aimed at formation of specifically responding (bio)active sensing layers and sample processing systems. This can be achieved particularly through formation of biorecognition layers using natural or synthetic (bio)receptors deposited on active area of the transducer, and microfluidic based systems for bioassays. Particular interests are focused on development of sensor and microfluidic based bioanalytical microtools for brain metabolites analysis and non-specific and specific markers of cardiovascular and Alzheimer diseases as well as for bioactive substances (cytostatics, psychoactive drugs). These include recent and perspective research concerning microfluidic based systems for biomedical applications, in particular for determination of selected markers in biological samples of very small volume, such as cell lysates. A future direction of the research is related to theranostics, integrating many technologies, such as organs-on-a-chip,  and microanalytical tools for monitoring the cell cultures.